3. Granulation, a technique of particle enlargement by agglomeration, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. During the granulation process, small fine or coarse particles are converted into large agglomerates called granules. Pelletization is a worldwide process used in producing artificial aggregates although its usage is not common in Turkey. In this study, lightweight aggregates (LWAs) were manufactured through cold-bonding pelletization of ground granulated blast furnace slag (G) and two types of fly ash with different finenesses (Fly ash A and B). Ordinary Portland cement (PC) was used as a binder at varying Division of Pharmaceutical Technology, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, Athens 157 71, Greece; Telephone: (301) 727- 4023; Fax: (301) 727-4027; E-mail: rekkas@pharm.uoa.gr 1 Pelletization by means of wet granulation in a fluid-bed weight basis (dg) and the geometric SD (σg) were rotary processor is a The replacement of traditional and non-renewable resources by shifting towards renewable-based strategies is a strategy implemented by the European Union for a circular economy-based society. Among the various methods to produce renewable biofuels, hydrothermal carbonization is promising in terms of waste management. This technology involves thermochemical treatment of wastes at lower Flow chart of pelletization techniques. Pellets and pelletization: emerging trends in the pharma industry 1419. sions. Rod shaped extrudes are prepared with suit-. able plasticity. Plasticity They are generally produced via a pelletization process whereby a powder Pellets are spherical or nearly spherical, free-flowing granules with a narrow size distribution, typically varying between 500 and 1500 µm for pharmaceutical applications. Granulation is defined as the size enlargement process in which fine and smaller particles are aggregated to form strong and stable particles called granules. Present article mainly focuses on advanced granulation techniques such as moisture activated dry granulation, thermal adhesion granulation, foam binder granulation etc. As a result, the present level of slimes generation has reduced to 6–7% against 12–14% a few years back. Second is to explore possible avenues for economical utilization of slime including utilization of slimes in pelletization, smelt reduction process (Hismelt & Romelt), Iron making Technology Mark 3 (ITMK3) process etc. 3. • Rotary tablet press is a mechanical device that unlike the single punch tablet press. • Tooling station helps in compress granules/powder mixture into tablets. • Upper and lower punches leaving the powder granules to be compressed in the middle. • It was developed to increase the output Of tablets. 0Bn22.

difference between granulation and pelletization